These Milk Thistle Supplements Could Make a Difference if You Have NAFLD

After being diagnosed with a fatty liver disease, everything I ate, drank, and did felt like a direct threat to my liver’s health. But amidst all the worries, one recommendation from my hepatologist stood out: Milk Thistle supplements.

Overwhelmed by the endless options and sometimes exaggerated claims online, I did the homework myself. After years of personal experience and research, I’m sharing everything I learned, saving you the stress and uncertainty.

I managed to reverse my NAFLD, and I believe milk thistle was a key ally in my journey. I wrote everything about it in my book, From Fatty Liver to Healthy Liver – make sure to read it if you want to see everything that worked for me.

(Please note: I get commissions for purchases made through links in this article.)

Back to today’s topic, here’s a straightforward, genuinely helpful look at the three best milk thistle supplements for fatty liver, why I trust them, and how they could help you. Here’s the quick summary:

• Liver Support Plus (which has a blend of milk thistle, artichoke, and other herbs and minerals that help the liver.)
• Puritan’s Pride Milk Thistle (just Milk Thistle extract – 1,000mg.)
• Nature’s Bounty Milk Thistle (Milk Thistle extract alternative)

Now let’s get a bit more in depth in terms of what options you have and which are, in my opinion, the best Milk Thistle you should take.

Liver Support Plus – Top Choice

For those looking for a complete liver boost rather than milk thistle alone, Liver Support Plus is a solid choice. It blends milk thistle with minerals like zinc and herbs like artichoke, beetroot, and chicory root, plus various extracts intended to support overall liver health.

Although slightly below the ideal milk thistle dosage, it compensates with all the other herbs and minerals included in the mix.

While I am usually cautious about herbal mixes because I prefer science-backed data, the health and science media backs up at least some of the ingredients used in Liver Support Plus (you can check everything on the supplement’s website). It’s also manufactured in the US – another positive thing, in my opinion.

Also, plenty of users report positive experiences, and it could be an excellent option for anyone seeking broader liver support.

Click here to check it out

Puritan’s Pride Milk Thistle – Excellent Alternative

This one is one of the bestselling products on Amazon at the moment of writing, offering great quality at a low price. You simply can’t ask for much more!

Puritan’s Pride Milk Thistle Extract brings the trust of a recognized brand along with the precise daily recommended dose (250mg – the equivalent of 1,000mg milk thistle, which is the exact daily dose recommended by my doctor.)

The pack comes with 180 softgels, enough to last half a year, making it convenient and budget-friendly.

Manufactured in the USA, this supplement ticks all the right boxes: potency, reputation, and affordability. After all, you can’t get so popular without offering true quality in return!

Check price at Amazon

Nature’s Bounty Milk Thistle

This is another solid milk thistle supplement for fatty liver disease. It has exactly the dose recommended by my doctor and one container has 200 capsules – so a bit more than 6 months of supply.

Plus, we’re talking about a Nature’s Bounty product – these are always of high quality and this particular one is, at the moment of writing, having a score of 4.7 stars out of 5 on Amazon (which is a really high rating).

Back to this silymarin supplement, it is made in the USA and is safe to use. A good choice if you want a larger quantity from a better-known brand. In other words – an amazing pick overall.

Check price at Amazon

Clinical studies, such as those reported by the National Institutes of Health (NIH), have shown milk thistle’s active compound, silymarin, helps reduce inflammation and liver enzyme levels in patients with fatty liver disease.

In the end, it’s up for you to decide which of these supplements to take – ideally, after talking to your doctor.

But even if you start taking them, you still need to stick to your diet and continue changing your lifestyle, as these supplements alone are not a replacement for good eating, drinking, and living habits!

How to take milk thistle if you have a fatty liver?

My doctor’s recommendation was to take one pill with 250mg of Milk Thistle extract every morning for 90 days, then take a break for 1 month, and then repeat. However, immediately after being diagnosed, my doctor recommended taking 500mg daily for the first month to speed up the recovery early on.

You can go up to two pills per day, but it’s always best to just ask your doctor as they know better based on your situation.

IMPORTANT! When taking these supplements, keep this in mind: although silymarin (aka milk thistle) has been always associated with improved liver functions and has been praised for its healing effects over the liver, it won’t do wonders by itself.

In other words, this is not a medicine that will reverse your fatty liver alone. You still need to stick to your diet, lose weight (if needed) and exercise in order to make it happen. Milk thistle is said to help and probably does, but it’s not the cure.

However, any extra help is welcome – that is always my motto – so why not give your liver an even better and bigger boost?

They are cheap and, at worst, they won’t have any effect. But if science-backed studies are correct, they will help your recovery a lot.

Are There Any Side Effects?

Milk thistle supplements are usually safe, but mild stomach upset, nausea or allergic reactions can occur occasionally. Always consult a healthcare provider, particularly if you take medications or have allergies to similar plants like ragweed or daisies.

I Carefully Selected These Supplements

When evaluating milk thistle supplements, I did not rely only on Amazon ratings or popularity alone. Here are the criteria I used:

• Personal experience: As a former NAFLD patient myself, I took various milk thistle supplements and liver boosters over the years.
• Potency and Dosage: Recommendations directly from hepatologists are typically around 250mg/day of silymarin (the active compound in milk thistle).
• Brand Reputation & Transparency: I prioritized supplements from trusted, transparent companies, ideally backed by independent lab testing.
• Value for Money: Supplements had to be reasonably priced without sacrificing quality.
• User Experience: I considered verified customer feedback to ensure real-world efficacy and satisfaction matched product claims.

The resulting recommendations above represent my personal opinion and there are no guaranteed results, although we have various studies confirming the usefulness of milk thistle in managing liver disease. (Read all about it here.)

Wrapping up

The journey to reversing fatty liver disease begins with informed decisions, dietary adjustments, and consistent habits.

Milk thistle, in my personal experience, is a powerful ally on this path – and one I’d comfortably recommend to friends, family, or anyone facing the challenge of NAFLD.

Each of the three supplements listed above is a great choice if you’re looking for supplements and I can only hope they will help you on your path to regaining your health.

And if you’re a fan of supplements and natural boosters, you can also check out my recommended magnesium supplements to help improve fatty liver disease, read about the benefits of apple cider vinegar, or the liver-friendly superfoods you should always consume.